SAA anticorps (Biotin)

N° du produit ABIN453894

Cet anticorps anti-SAA est un anticorps Souris Monoclonal détectant SAA dans EIA et ELISA (Detection). Adapté pour Humain.

Aperçu rapide pour SAA anticorps (Biotin) (ABIN453894)

Antigène: SAA (Serum Amyloid A (SAA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SAA est conjugé à/à la Biotin

Application: Enzyme Immunoassay (EIA), ELISA (Detection)

Clone: 607

Détail du produit anti-SAA anticorps (Biotin)

Specificité: This antibody reacts with natural and recombinant SAA. Does not show any cross-reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, TGF-beta and EGF.

Purification: Affinity Chromatography on Protein G

Immunogène: Highly purified recombinant Human SAA (MW: 12 kDa)

Isotype: IgG2a

Information d'application

Indications d'application: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0±0.1, 0.1 % Proclin-300, 1 % Gelatin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.

Détails sur SAA

Antigène: SAA (Serum Amyloid A (SAA))

Autre désignation: Serum Amyloid A Protein (SAA)

Sujet: The serum amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.Synonyms: SAA1, SAA2

ID gène: 6288

NCBI Accession: NP_000322

UniProt: P02735